MULTIOMICS ANALYSIS SERVICES
Your partner for integrative biomarker analysis & personalized diagnostic solutions
AIT Molecular Diagnostics – your one-stop shop for multi-omics analysis. From assay development to high-throughput processing, bioinformatics, and validation of findings – we provide end-to-end solutions from your biospecimens, fully tailored to your project needs
Multi-Omics Services Overview
The following table provides a structured overview of our core areas and analytical services:
Omics Layer
Analytical Services
Genomics
• Genotyping, mutation detection…
• Illumina-arrays & NGS
• NGS (Illumina, PacBio, Oxford Nanopore)
• tissue derived (e.g. FFPE) and liquid biopsy (cfDNA)
Epigenomics
• DNA-Methylation
• Illumina-arrays & NGS
• Biological Age
Transcriptomics
- RNA-Seq / tissue and bodyfluid derived
- miRNA / exosomal miRNA
- ncRNA
- mRNA
Proteomics & Immunomics
- Olink Proteomics (48-5400 targets)
- Antibody profiling with
- Protein- und Peptid-arrays
- Luminex Bead Arrays
- PhIP-NGS
Metagenomics
- Microbiome
- 16S/18S /ITS
- Resistances
- Metagenome
Metabolomics
- with our associated partners
- MassSpec based
- NMR based
Our Multi-Omics Services and beyond
We provide a comprehensive multi-omics portfolio and support experimental design, pre-analytics, samples manipulation (controlled handling, aliquoting, and tracking), bioinformatics, but can also provide confirmation and validation studies by targeted assays, providing support in assays setup and giving advice for efficient analysis to get a maximum output from your samples.
Unlock the full potential of your samples with our end-to-end multi-omics solutions. We support you from experimental design and sample logistics to advanced bioinformatics — ensuring your study is efficient, reproducible, and impactful.
Need targeted validation? We offer custom assay development, confirmation studies, and expert advice to help you get the most meaningful insights from your data.
Pre-analytics
- Sample preparation (e.g., DNA/RNA isolation)
- Quantification and quality control…
Genomics
- DNA genotyping and mutation-detection
- Illumina Global Screening Array v3/v4 – This array is part of our standard repertoire and any sample numbers can be processed.
- All other Illumina arrays can be provided.
- Next Generation Sequencing (NGS)
- Targeted and customized Assays for detection of low frequent mutations / alleles
- Whole Genome Sequencing (WGS)
- Available platforms: Illumina, PacBio, Oxford Nanopore Technology
Epigenomics
- Whole Genome DNA Methylation Analysis with various technologies including bioinformatics
- EPIC v2 Array (~930.000 CpG sites)
- TWIST Human Methylome Panel (3.98M CpG sites)
- Nanopore Methylation Sequencing
- Customized and targeted DNA methylation analysis
- NGS-based DNA-methylation-panels
- Amplification based (10-1000 plex)
- hybridization capture bead based customized approaches (10-100.000 plex)
- detection of e.g. 0.1% tumor DNA in background DNA
- customized MSRE-qPCR based panels (48-96 plex)
- AIT’s standard targeted 480 plex MSRE-qPCR-panel (Target list download)
- NGS-based DNA-methylation-panels
Transcriptomics
- Gene expression analyses (mRNA, miRNA, ncRNA)
- RNA sequencing (RNA-Seq) and targeted panels
- Transcriptomics of bodily fluid samples (liquid biopsy)
- Exosomal miRNA (200-500µl serum or plasma)
- Olink Explore and Olink Targeted Proteomics
- Antibody profiling
- Protein and peptide arrays (microarray- & Luminex® bead array- based)
- Array and NGS based proteome-wide formats using / providing AIT, CDI, KREX, InfinityBio as well as customized formats
- Antibody reactivity against pathogens (e.g. AIT’s 260x human pathogen array (serum antibody profiling associated with bacterial infections), viruses, allergens (e.g. VirScanTM, VirsigthTM, AllersigthTM…)
- 10-50µl Serum oder Plasma als startmaterial
- request for other sample types
Metagenomics
- complete metagenomic analyses (tissue, cfDNA)
- Microbiome characterization (e.g., gut, saliva)
- 16S/18S /ITS – analytics
- Antibiotics resistance detection
Our specialized analysis pipelines combine molecular data with clinical trial parameters:
- Assay Design & Validation
- Biostatistics & Visualization
- Disease Modelling & Network Analysis
- Multi-Modal e-Data Integration
- Customized Software Solutions
- Sample typesTissue (nativ und FFPE)
- Blood
- Cell cultures and supernatants thereof
- Liquid Biopsy
- Liquor
- Urine
- Saliva, …
Typical Fields of Application
- Early detection & prognosis (e.g. cancer, infections, autoimmunity)
- Therapy monitoring & companion diagnostics
- Development of non-invasive diagnostic tests (liquid biopsy )
- Project-accompanying omics analyses
- Contract research & study support
Our Services for you
- Tailor-made service packages for industry & research
- Validation projects, prototype development, software design under GLP-conditions
- Support at clinical Study planning & implementation
- Advice to Feasibility & study architecture
